| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_280d87031f0c5786de1808713a1b76b7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-924 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 |
| filingDate |
2003-08-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5eca62b5e39f89d690aa9233dbaccdd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_066f95d814a65a748bfbeab47603b374
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcbdabc36fd5aff8081ff023e0757aa4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e20bf4533052664164b9b25b2ec31557 |
| publicationDate |
2005-06-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1539154-A2 |
| titleOfInvention |
Methods for regulating transcription by targeting quadruplex dna |
| abstract |
Among the different intrastrand quadruplex structures that can arise from duplex DNA, it has been discovered that the nucleotide sequences (GGA)4 and (GGA)3GG form biologically significant quadruplex structures. Thus, provided herein are methods for identifying molecules that modulate the biological activity of quadruplex DNA comprising the nucleotide sequence (GGA)4 or the nucleotide sequence (GGA)3GG, and specifically, methods for identifying molecules that bind such quadruplexes. Also provided herein are methods for modulating the biological activity of a biologically significant native quadruplex DNA with a molecule identified by the methods described herein. |
| priorityDate |
2002-08-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |