http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1551459-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6925
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filingDate 2003-07-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_135f527c314f7702f48f19dd6e73c374
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fb1343fb8de2961e1cdf31f93edba4e
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publicationDate 2005-07-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1551459-A1
titleOfInvention Microbubble compositions, and methods for preparing and using same
abstract Described are microbubble compositions including microbubbles having membranes that incorporate modified surface features that may be useful, for example, in facilitating binding to a target surface or substance. The surface features may include non-spherical attributes such as crenations, folds, projections, or wrinkles, which can increase the deformability of the microbubble membrane. Such microbubble compositions can be incorporated into targeted ultrasound contrast agents and methodologies. Methods for preparing modified microbubble compositions include providing microbubbles having spherical membranes, and converting the spherical membranes to non-spherical membranes having surface features as mentioned above. Targeting substances can be incorporated into the membranes before or after their conversion from spherical to non-spherical forms.
priorityDate 2002-07-11^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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