http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1582517-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7b85edf4e8b9338b24ad34ce53c7328 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2004-01-09^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f49e4c2028601941a124c0d6181d55 |
| publicationDate | 2005-10-05^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1582517-A1 |
| titleOfInvention | Blood-brain barrier disruption inhibitors |
| abstract | An object of the present invention is to provide a blood-brain barrier disruptionninhibitor. The present invention provides a blood-brain barrier disruption inhibitornwhich comprises as an active ingredient a pyrazolone derivative represented by thenfollowing formula (I) or a physiologically acceptable salt thereof, or a hydrate thereof orna solvate thereof:n nwherein R 1 represents a hydrogen atom, an aryl group, an alkyl group, or annalkoxycarbonylalkyl group; R 2 represents a hydrogen atom, an aryloxy group, annarylmercapto group, an alkyl group or a hydroxyalkyl group; or R 1 and R 2 are combinednwith each other to represent an alkylene group; and R 3 represents a hydrogen atom, annalkyl group, a cycloalkyl group, a hydroxyalkyl group, a benzyl group, a naphthyl group,na phenyl group, or a phenyl group substituted with 1 to 3 substituents selected from thengroup consisting of an alkyl group, an alkoxy group, a hydroxyalkyl group, annalkoxycarbonyl group, an alkylmercapto group, an alkylamino group, a dialkylaminongroup, a halogen atom, a trifluoromethyl group, a carboxyl group, a cyano group, anhydroxyl group, a nitro group, an amino group and an acetamide group. |
| priorityDate | 2003-01-10^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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