| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd727aa2b4e6c347aadd94971881d671 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6881 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate |
2004-04-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d8fe4534227348c37828c8deb8f267b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2baf236be8801a8903d4d80b8153692f |
| publicationDate |
2006-01-18^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1617215-A1 |
| titleOfInvention |
Method of evaluating oxidized protein in horny cell layer |
| abstract |
The invention provides a method for two-dimensional evaluation of the nature of horny layer oxidized protein on a horny layer, the method comprising specific fluorescent labeling of the carbonyl groups of the oxidized protein in a horny layer specimen taken from skin, and detection of the fluorescence for evaluation, as well as a kit used to carry out the method and a method for screening of agents which inhibit increase in oxidized protein. The invention further provides a method for detecting the oxidized form of a cornified envelope consisting of the water-insoluble substances in a skin-derived horny layer specimen, the method comprising specific fluorescent labeling of the carbonyl groups in a cornified envelope in the oxidized form and detection of the fluorescence thereof for evaluation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1722224-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632633-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1722224-A4 |
| priorityDate |
2003-04-21^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |