| abstract |
The present invention provides methods for the treatment or prevention of a viral, bacterial, or fungal infection using an anionic cellulose- or acrylic-based polymer, a prodrug thereof, or a pharmaceutically acceptable salt of said anionic cellulose based polymer or acrylic based polymer or prodrug of either. The present invention also provides pharmaceutical compositions comprising an anionic cellulose or acrylic based polymer, a prodrug thereof, or a pharmaceutically acceptable salt of said anionic cellulose-based polymer or prodrug. The present invention further provides combination therapies for the treatment or prevention of a viral, bacterial, or fungal infection using an anionic cellulose or acrylic-based polymer, a prodrug thereof, or a pharmaceutically acceptable salt of said anionic cellulose based or acrylic based polymer or prodrug of either and one or more anti-infective agents. The present invention also provides inventive anionic cellulose- or acrylic-based polymers which can be used in the above-mentioned methods, pharmaceutical compositions, and combination therapies. Those inventive anionic cellulose- or acrylic-based polymers are molecularly dispersed and mostly dissociated in an aqueous solution at pH ranging from about 3 to about 14. |