| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68cfa36b88a3869912ccc31dab628643 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-49 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-48 |
| filingDate |
2007-04-11^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43d1db9ac5a798eab6cb3f3e754a0b72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dabbd9df132ab50af0863898ef2bf9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d786c21207cd244e00fd34b6a33bded
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b611162eafe646b92a1453e94bfd9e3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b95fe41425b71730b00aff23c0171e54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba1949fcaaea119e88511ec1ae267ca4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f0c4c70b307c634164e4880cb91ae20 |
| publicationDate |
2007-10-17^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1845083-A2 |
| titleOfInvention |
New arylsulfonohydrazide inhibitors of enzymes MurC and MurD |
| abstract |
This invention belongs to the field of pharmaceutical chemistry and relates to new arylsulfonohydrazides as inhibitors of UDP- N -acetylmuramyl:L-alanine ligaze (MurC) and UDP-N-acetylmuramyl-L-alanine:D-glutamate ligaze (MurD), to procedures for their preparation and pharmaceutical preparations containing the same. The enzymes MurC and MurD are the key enzymes involved in the synthesis of bacterial peptidoglycan, so arylsulfonohydrazide inhibitors possess antibacterial activity. Compounds of general formula In nand the pharmaceutically acceptable salts are described. The appropriate substituents are clearly presented in the body of the text and in claims. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017654-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7939564-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8907131-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008136976-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8703749-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9156783-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8455686-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011070444-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093425-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651310-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651310-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7652168-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008136976-A3 |
| priorityDate |
2006-04-13^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |