http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1877060-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b6121dedd894b3f760906b68697d616
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55
filingDate 2006-04-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_100402df668e52782960773fc2955080
publicationDate 2008-01-16^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1877060-A2
titleOfInvention Therapeutic bifunctional compounds
abstract The invention generally relates to systems and methods for treating inflammatory and proliferative diseases, enabling treatment of MDR tumor cells by using a bifunctional compound that inhibits both fatty acid metabolism and glycolysis. Thus, the invention links a fatty acid metabolism inhibitor to a glycolysis inhibitor. More particularly, the invention provides novel bifunctional compounds that link a moiety having the functionality of an oxirane carboxylic acid compound to a moiety having the functionality a glucose derivative. In specific embodiments, the invention provides a bifunctional compound that links a moiety having the functionality of etomoxir to a moiety having the functionality of 2-deoxy-D-glucose.
priorityDate 2005-04-28^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21802
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14967
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID43116
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24590
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3000671
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID25271863
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID365701
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6437358
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID56841910
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5284558
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID13342
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID108161
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10486757
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24281
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID188405
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID108223
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9919910
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135447984
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5995
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10819
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID108144
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID42871
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25335
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135409400
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID54949
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID66856926
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID3086164
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16078
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID134688829
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID164528
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID66672688
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID57352253
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280956
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID49866635
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID398022
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5284454
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID2331
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID2107
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6451
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID368517
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID244989
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID451668
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID368516
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID2800
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID59693
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5453

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