| abstract |
The invention relates to the field of pharmacology. More specific, the invention relates to a controlled release composition. n This invention is related to a controlled release composition comprising a cross-linked gelatin and at least one therapeutic protein wherein the ratio of the average mesh size (ξ) of the gelatin matrix and the average hydrodynamic radius (R H ) of the therapeutic protein is smaller than 2, preferably smaller than 1.5. |