Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_526367fab1540e711277e0be832380a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbe675b46d686407d64e31a937562663 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2009-03-05^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07716da5dc6005217ebb271384b9b13f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d735e5da698e7e634b420a1888b23640 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0836aad7d147e3dd9186c6672b1b8d7b |
publicationDate |
2010-09-08^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2226080-A1 |
titleOfInvention |
Antagonistic peptides for frizzled-1 and frizzled-2 |
abstract |
The invention is in the field of molecular medicine. It provides antagonistic compounds for frizzled1 and/or frizzled-2 receptors which may be useful in molecular imaging of the wound healing process after myocardial infarction and in therapeutic intervention into wound healing after remodeling of the heart, thereby ameliorating the consequences of myocardial infarction. The invention provides a method for antagonizing frizzled-1 or frizzled-2 receptors wherein the receptor is contacted with a composition comprising a linear fragment of Wnt3(a) or Wnt5a or a functional analogue thereof which comprises at least one cysteine residue, one threonine residue, one aspartic acid residue and one glycine residue. |
priorityDate |
2009-03-05^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |