http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2393486-A1

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filingDate 2009-04-29^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d663135f0c46801e18df65636045fd0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfbe49ae4ff526d88f8b5bb34951ec4a
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publicationDate 2011-12-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2393486-A1
titleOfInvention Aceclofenac-containing controlled-release oral drug preparations and their manufacturing process
abstract Disclosed herein are single-layer and double-layer tablets, which release aceclofenac in a controlledmanner so as to achieve ideal drug release close to a straight line. Also, the tablets promote drug absorption in the stomach by controlling pH, contain aceclofenac with improved stability and haveboth immediate-release properties and sustained-release properties. Specifically, provided is an aceclofenac sustained-release tablet which is composed of an immediate-release layer containing aceclofenac, a water-soluble additive, a pH-controlling agent, a disintegrant, a filler and a lubricant and of a sustained-release layer containing aceclofenac, a release-controlling polymer, an oil-soluble surfactant, a filler and a lubricant, wherein the pH-controlling agent is sodium hydrogen carbonate, and the release-controlling polymer is a mixture of hydroxypropylmethylcellulose and carbomer.
priorityDate 2009-02-04^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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