http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2393486-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_143ac4fbe1e063c6a828a96cfffc34d5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 |
filingDate | 2009-04-29^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d663135f0c46801e18df65636045fd0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfbe49ae4ff526d88f8b5bb34951ec4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f959841ff0173f7d47f43ac91944ad13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2613f3cb3e17a8d57299555b439e8d0d |
publicationDate | 2011-12-14^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-2393486-A1 |
titleOfInvention | Aceclofenac-containing controlled-release oral drug preparations and their manufacturing process |
abstract | Disclosed herein are single-layer and double-layer tablets, which release aceclofenac in a controlledmanner so as to achieve ideal drug release close to a straight line. Also, the tablets promote drug absorption in the stomach by controlling pH, contain aceclofenac with improved stability and haveboth immediate-release properties and sustained-release properties. Specifically, provided is an aceclofenac sustained-release tablet which is composed of an immediate-release layer containing aceclofenac, a water-soluble additive, a pH-controlling agent, a disintegrant, a filler and a lubricant and of a sustained-release layer containing aceclofenac, a release-controlling polymer, an oil-soluble surfactant, a filler and a lubricant, wherein the pH-controlling agent is sodium hydrogen carbonate, and the release-controlling polymer is a mixture of hydroxypropylmethylcellulose and carbomer. |
priorityDate | 2009-02-04^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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