Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9462554eae2ed2d51c622f9837ef20d5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-644 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 |
filingDate |
2008-04-28^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebf5a6a81edde560ef19fbffcf7d9734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f686600db39d9f5746e8a6e9654e6392 |
publicationDate |
2012-10-31^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-2517714-A1 |
titleOfInvention |
Recombinant vitamin K dependent proteins with high sialic acid content and methods of preparing same |
abstract |
Methods of isolating highly sialylated recombinant vitamin K dependent proteins, particularly Factor IX, by chromatographic methods are described. The highly sialylated recombinant proteins are characterized. The improved Factor IX has at least 62% N-glycosyslation with 3 or 4 sialic acid residues and improved bioavailability and pharmokinetic properties. |
priorityDate |
2007-04-26^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |