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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2365a12badb72780768a21020a087826
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publicationDate 2012-11-07^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2519816-A2
titleOfInvention Method for discovering pharmacologically active substance of natural products using high resolution mass spectrometry and pharmacological activity test
abstract Disclosed is a method for discovering pharmacologically active substances from natural products at high speed, including: obtaining an activity profile by testing pharmacological activity of a plurality of samples; obtaining a mass profile based on a mass spectrum resulting from analysis of the samples by mass spectrometry; and determining molecular weight of pharmacologically active substances by comparing and analyzing the activity profile and the mass profile. The disclosed method allows fast discovery of pharmacologically active substances by performing high resolution mass spectrometry for numerous components included in an extract sample of natural products and comparing with the activity test data. The information about the intensity of the activity of the pharmacologically active substances of the natural products allows effective utilization of the natural products.
priorityDate 2009-12-29^^<http://www.w3.org/2001/XMLSchema#date>
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