http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2623098-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbd1d44888f5b41142d83de455096387 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 |
| filingDate | 2012-02-03^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d859a6b0f56937a8de60f9cfbeb0b7bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f42f2c945d62629cdcc160105dde425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1cb6ed23e9ebb22407e824785d13271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9046a6c5dee99660685862c8c594f9ed |
| publicationDate | 2013-08-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-2623098-A1 |
| titleOfInvention | Amide Amino Acid Esters of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) as Potent Inhibitors of Colon Tumor Cell Growth |
| abstract | The present invention refers to amides of NSAIDs, preferably of naproxen, amino acids esters having the chemical structure of formula In nwherein R 2 is an amino acid ester residue, or any racemic form, prodrug, enantiomer, or analog of the substance, or pharmaceutical composition comprising such compound, for use as a medicament for the treatment or prevention of cancer or a proliferative disease or disorder. Preferably, the compounds may be used for the treatment or prevention of colorectal cancers. The invention also comprises methods for the treatment or prevention of a proliferative disease or disorder, comprising administering to a mammal in need thereof an effective amount of a therapeutic agent, wherein the therapeutic agent comprises such amide of naproxen amino acids esters. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108578399-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108578399-B |
| priorityDate | 2012-02-03^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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