http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2831241-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ae7bc470b590116f17769a5b53f38cc
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
filingDate 2013-03-27^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fd25d95c67f3868e2dcf0dbad3e1158
publicationDate 2015-02-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2831241-A1
titleOfInvention Artificial nucleic acid molecules for improved protein or peptide expression
abstract The invention relates to an artificial nucleic acid molecule comprising at least one 5'UTR element which is derived from a TOP gene, at least one open reading frame, and preferably at least one histone stem-loop. Optionally the artificial nucleic acid molecule may further comprise, e.g. a poly(A)sequence, a poyladenylation signal, and/or a 3'UTR. The invention further relates to the use of such an artificial nucleic acid molecule in gene therapy and/or genetic vaccination.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4035659-A1
priorityDate 2012-03-27^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID128725069

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