abstract |
A monoclonal antibody, characterized in specifically binding to three, four or five antigens e.g. human c-Met, IGF-IR, EGFR, HER2 and/or HER3, is useful for the manufacture of a pharmaceutical composition and especially for the treatment of cancer, especially breast, colon, lung, or pancreatic cancer. A method using immunization of rabbits and selection of single B cells is useful for the production of such antibodies. |