http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2930246-A1

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publicationDate 2015-10-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-2930246-A1
titleOfInvention Novel single nucleotide polymorphisms associated with various diseases and disorders
abstract The present invention relates to a method for identifying an individual who benefits from a high omega-3-fatty acid (n-3-FA) diet when being afflicted with certain diseases or indispositions. The method comprises the detection of at least one specific nucleotide at a single nucleotide polymorphism position in a nucleic acid sample obtained from an individual. The presence of one or more of the nucleotides at the corresponding single nucleotide polymorphism positions in the sample indicates that the respective individual benefits from an n-3-FA diet when being afflicted with certain diseases or indispositions, such as cancer. The present invention also provides methods for determining the responsiveness of a cancer disease to a high n-3-FA diet and for identifying individuals having a reduced risk of developing an aggressive cancer type and/or metastasis when being subjected to a high n-3-FA diet. Kits for the detection of the nucleotides at the corresponding single nucleotide polymorphism positions of the present invention are also provided.
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