| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6e155fbc4f5769ab6553686affb39af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C53-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C55-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 |
| filingDate |
2015-01-30^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36a15aeae48d5feefe66b7bcb483a084
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cea0f65341dd553854d93554fae1ac1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d25e8cd5f4aea44b4437d520749cef39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_314f3901339c3fe94115c0825e5a10dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b657baa1d3f02a6e57c87109e51ab1ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_806f4fa2ac0b4448fdfd7749f8b9a3ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39fab4283f1e03eff2b61396901e8eb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5dcae04d39df0383275d2e507cae4fbf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_294c3b4baa648805570392d1b6f8ca30 |
| publicationDate |
2016-12-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3099669-A1 |
| titleOfInvention |
Process for the preparation of vortioxetine salts |
| abstract |
The invention relates to an improved process for the preparation of pharmaceutical active ingredients and also to high purity salts and pharmaceutical compositions prepared by said process. More particularly the invention relates to an economical process for the preparation of the compound having the international non-proprietary name (INN) vortioxetine and the chemical nomenclature l-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]-piperazine. Vortioxetine corresponds to the following Formula Still more particularly the invention relates to the preparation of high purity vortioxetine L- (+)-mandelate salt of the Formula IX, the conversion of this salt into other highly pure salts and also to the formulation of said salts. |
| priorityDate |
2014-01-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |