http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3180347-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 |
| filingDate | 2015-08-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2a912a213e3ce4f5988b0c920d0eee2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90bb341c9420c7283933f7c849a98b1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6110d9bc123bb2b68138713c723628d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0dfe5c8455a638bf1cd5d66bb580940 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0fbae0fb111f77921d6d0f686919a91 |
| publicationDate | 2017-06-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3180347-A1 |
| titleOfInvention | Synthesis of cephalosporin compounds |
| abstract | Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction. Provided herein are methods for the synthesis of cephalosporin compounds of formula (I) employing a palladium-catalyzed alkylation reaction, as well as compositions related to the same. In an aspect, provided herein is a method for preparing a compound of formula (II), or a salt thereof, comprising the step of admixing, e.g., reacting, a compound of formula (III), or a salt thereof, with a nucleophile (Nuc) in the presence of reagents comprising: (a) a palladium source; and (b) a palladium-binding ligand, to form a compound of formula (II), or a salt thereof. |
| priorityDate | 2014-08-15^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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