http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3191447-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-088 |
| filingDate | 2015-09-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48b6fa5a503152e47d9d707cda3d0e5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7b7aaf9795d9eeee9ae5a96c9db65b8 |
| publicationDate | 2017-07-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3191447-A1 |
| titleOfInvention | S-imino-s-oxo iminothiazine compounds as bace inhibitors, compositions, and their use |
| abstract | In its many embodiments, the present invention provides certain C-6 spirocarbocyclic iminothiadiazine compounds, including compounds Formula (I): or a tautomer thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein R 1A , R 1B , R 2A , R 2B , R 2 , R 3 , R N , ring A, R A , m, ring B, R B , and n are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed. |
| priorityDate | 2014-09-12^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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