| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bfedd66c70f37cb5168ccf8dc5d633d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-00032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
2012-07-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c440bdb2cade6884db477140511ad7f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5ba5722a4b7ed830f25004507570988
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ef1fad9a2af29486dd126cc8b1fab59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18bafe837214c71a424d0c68ff3b7e9a |
| publicationDate |
2018-03-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3290055-A2 |
| titleOfInvention |
Recombinant virus products and methods for inhibition of expression of dux4 |
| abstract |
The present invention relates to RNA interference-based methods for inhibiting the expression of the DUX4 gene, a double homeobox gene on human chromosome 4q35. Recombinant adeno-associated viruses of the invention deliver DNAs encoding microRNAs that knock down the expression of DUX4. The methods have application in the treatment of muscular dystrophies such as facioscapulohumeral muscular dystrophy. |
| priorityDate |
2011-07-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |