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filingDate 2018-12-13^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b8409c8b495deffb6f3dddea49845a
publicationDate 2019-06-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3498308-A1
titleOfInvention Complex comprising a psma-targeting compound linked to a lead or thorium radionuclide
abstract The present invention relates complexes comprising a prostate-specific membrane antigen (PSMA) targeting compound linked to a radionuclide, such as 212 Pb or 227 Th, through a TCMC or DOTA chelating moiety. These compounds, and pharmaceutical compositions comprising them, can be used for medical applications. These applications include the treatment of prostate cancer, and the complexes allow for dual targeting of cancers.
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