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filingDate 2017-10-26^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8b3d17fd70c7c66bd4292b454c86420
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b6e7e27cedb5f02c95fb5c0338cf5f1
publicationDate 2019-09-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3532059-A1
titleOfInvention Bromodomain and extra-terminal protein inhibitor combination therapy
abstract The present disclosure relates generally to compositions and methods of treating neoplastic diseases or cancers, such as glioblastoma and non-Hodgkin's lymphomas, or other cancers in which the subject suffers from an advance solid tumor, comprising a combination of, or administering a combination of, a bromodomain and extra-terminal protein BET inhibitor and at least on echemotherapeutic agent, which does not inhibit BET directly. The BET inhibitor/chemotherapeutic agent combination, or combination therapy, can yield syngergistic effects, thereby increasing the effectiveness of the cancer treatment as compared with the administration of either the BET inhibitor or the chemotherapeutic agent alone.
priorityDate 2016-10-27^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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