| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6baba7c6ceb747e544d919b5a53098e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-388
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-065 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0036 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-00 |
| filingDate |
2019-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c50ce985bcdc0129890cc5ddc4ee110 |
| publicationDate |
2020-05-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3654364-A1 |
| titleOfInvention |
Methods for multiplexed ms-3 analyses of peptides |
| abstract |
A method comprises: obtaining a precursor mass-to-charge value, ( m / z ) p , of a target precursor ion having formula [M + 2A] 2+ , M being a peptide molecule and A being one or more adducts; generating ions from a sample by an ion source; purifying and fragmenting ions comprising the ( m / z ) p , thereby generating a plurality of MS-2 species; co-purifying and co-fragmenting a selected subset of the MS-2 species, thereby generating a plurality MS-3 species, wherein each selected MS-2 species is a y-type ion species comprising a respective ( m / z ) f that is greater than ( m / z ) p ; mass analyzing the MS-3 species and selecting a subset thereof, each selected MS-3 species comprising a respective ( m / z ) g that satisfies a mass-to-charge selection criterion; and determining a quantity of the peptide from a summation of mass spectral intensities corresponding to the selected MS-3 species. |
| priorityDate |
2018-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |