http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3743429-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02ebace3075422b746e99a8d79920925 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2019-01-17^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3503a98bda629f5023751ab0d678a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aefb0bee75cb2108d3f0c59caef8e12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3d2ecab191f984cb334d58218b4e4d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c97fd52083ef23d5c7667c4d28c2e8 |
| publicationDate | 2020-12-02^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3743429-A1 |
| titleOfInvention | TRIAZOLE, IMIDAZOLE AND PYRROLE CONDENSED PIPERAZINE DERIVATIVES AND THEIR USE AS MODULATORS OF mGlu5 RECEPTORS |
| abstract | Disclosed are triazole, imidazole and pyrrole condensed piperazine derivatives and their use as allosteric modulators of mGlus receptor activity, pharmaceutical compositions comprising such compounds, and methods of treatment therewith. Compounds of the invention can be used for the treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline, dementia or cognitive impairment, or other pathologies that can be related either directly or indirectly to glutamate dysfunction, i.e., disorders treatable by positive allosteric modulation (PAM) or by negative allosteric modulation (NAM) of mGluR5. |
| priorityDate | 2018-01-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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