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filingDate 2016-09-23^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc6660afa10fc17490c872180988f1df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f71a7b78b66e387871e028ccdaecfd34
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publicationDate 2022-01-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3939606-A2
titleOfInvention Improved methods and compounds for eliminating immune responses to therapeutic agents
abstract The invention describes kit of parts of polypeptides comprising:a) a peptide comprising :a1) an MHC class II T cell epitope or a CD1d-restricted NKT cell epitope, and a2) immediately adjacent to said epitope or separated by at most 7 amino acids from said epitope a [CST]-X(2)-C [SEQ ID NO:7] or C-X(2)-[CST] [SEQ ID NO:8] oxidoreductase motif sequence,andb) a polypeptide comprising:b1) a therapeutic protein andb2) the epitope defined in a1), wherein the epitope sequence is a sequence which differs from the sequence of the protein of b1).The therapeutic protein, in combination with the peptide, is used to prevent an immune response against the therapeutic protein.
priorityDate 2015-09-25^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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