http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3972993-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70528
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725
filingDate 2020-05-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72558524cf57c14d08629019f12ee7eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32470d8e5144a56d7076c071a7f6c119
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_852f51399a1c8ec1be53c3a80d2d802e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cdaade4db992b679c6eb26758ccc725
publicationDate 2022-03-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3972993-A1
titleOfInvention Variant cd58 domains and uses thereof
abstract The present disclosure provides CD2 binding molecules that specifically bind to CD2, including monospecific, bispecific and trispecific binding molecules, conjugates comprising the CD2 binding molecules, and pharmaceutical compositions comprising the CD2 binding molecules and the conjugates. The disclosure further provides methods of using the CD2 binding molecules to modulate CD2 signaling in order to treat a variety of immune (e.g., autoimmune), inflammatory and proliferative disorders. The disclosure yet further provides recombinant host cells engineered to express the CD2 binding molecules and methods of producing the CD2 binding molecules by culturing the host cells under conditions in which the CD2 binding molecules are expressed.
priorityDate 2019-05-21^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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