http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3972993-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70528 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725 |
filingDate | 2020-05-19^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72558524cf57c14d08629019f12ee7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32470d8e5144a56d7076c071a7f6c119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_852f51399a1c8ec1be53c3a80d2d802e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cdaade4db992b679c6eb26758ccc725 |
publicationDate | 2022-03-30^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3972993-A1 |
titleOfInvention | Variant cd58 domains and uses thereof |
abstract | The present disclosure provides CD2 binding molecules that specifically bind to CD2, including monospecific, bispecific and trispecific binding molecules, conjugates comprising the CD2 binding molecules, and pharmaceutical compositions comprising the CD2 binding molecules and the conjugates. The disclosure further provides methods of using the CD2 binding molecules to modulate CD2 signaling in order to treat a variety of immune (e.g., autoimmune), inflammatory and proliferative disorders. The disclosure yet further provides recombinant host cells engineered to express the CD2 binding molecules and methods of producing the CD2 binding molecules by culturing the host cells under conditions in which the CD2 binding molecules are expressed. |
priorityDate | 2019-05-21^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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