http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3999662-A1

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
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filingDate 2019-07-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59e4dd8538fd1f661adcb572b5099250
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7a7798502024953d0db57a8a809732c
publicationDate 2022-05-25^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3999662-A1
titleOfInvention Characterization of prostate cancer using dna methylation assay system
abstract The present invention (PROMESYS) relates to methods and tools for diagnosis and prognosis of prostate cancer, patient monitoring/follow-up and prediction of response to treatment of patients with confirmed diagnosis of prostate cancer. The methods conducted in vitro comprise the steps of providing a tissue and/or a body fluid sample, obtained from an individual, and determining DNA methylation status and/or level of one or more genes selected from the group consisting of PRKCB, ADAMTS12, NAALAD2, FILIP1L, ZMIZ1 and KCTD8 in a sample. Additionally, methylation status and/or level of CCDC181, MT1E, APC and/or RASSF1 can be included in the biomarker panel for improved performance. Furthermore, the present invention refers to kits and oligonucleotides for use in such a method.
priorityDate 2019-07-19^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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