abstract |
PROCEDURE FOR PREPARING QUINAZOLINONE DERIVATIVES. UNDERSTAND TO OBTAIN A COMPOUND OF FORMULA (I), (A) REACT (III) WITH A LOWER ALKYLAMINE OR AMMONIA, (B) IF NECESSARY, SUBMIT THE PRODUCT OBTAINED IN (A) TO AN INTRAMOLECULAR CYCLE, (C) OPTIONAL , FORM A SALT OF THE PRODUCTS RESULTING FROM (AYB). IN THE FORMS RBS1 IS LOWER ALKYL OR HYDROGEN, RBS2, RBS3, RBS4 AND RBS5 (EQUAL OR DIFFERENT BETWEEN THEM) ARE HYDROGEN, HALOGEN, LOWER ALKYL OR ALCOXI R5, AND 2 IN R4 FORMING A LOWER ALKYLENDIOXI GROUP AND THE TWO REMAINING GROUPS REPRESENT HYDROGEN ATOMS. THIS PROCEDURE FOR THE OBTAINING OF (III) HAS APPLICATION ON AN INDUSTRIAL LEVEL WITH MANY ADVANTAGES BECAUSE NO LOSSES OF INTERMEDIATE PRODUCTS IN INSULATION AND PURIFICATION STAGES, WITH A GLOBAL PERFORMANCE OF OVER 70%. |