| abstract |
New derivatives of hydrazide, its preparation procedure and the pharmaceutical compositions containing them. Compounds of formula (I): R-NH-A-CO-NH-NH- (CO) {sub, n} -Z (I) in which: - n equals 0 or 1, - Z represents a group selected from aryl aryl-alkyl, heteroaryl and heteroaryl-alkyl optionally substituted, - R represents a group selected from: Z {sub, 1} -T-CO-, Z {sub, 1} -OT-CO-, Z {sub , 1} -TO-CO-, Z {sub, 1} -TS (O) {sub, q} - in which -Z {sub, 1}, T and q are as defined in the description, - A represents an alkylene, alkenylene, alkynylene of 3 to 8 carbon atoms, alkyl-cycloalkylene cycloalkylene-alkylene, alkyl-cycloalkylene-alkylene group, a group ** Formula ** in which B {sub, 1} is as it is defined in the description or in the form with the adjacent nitrogen atom a group ** Formula ** as defined in the description. Medicines. |