http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2188225-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate | 1999-08-13^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-06-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0735a0bdceb95bfcba712bd41398e67c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c79e381ff4d64f98c0451eb4b220e1e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28cb05fe5f659988a9465d58d81d11d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e3b6814efe4c4726ee1973b9eddcc2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdcb3a8673f5639d5e806aed430a18df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_692f42a1ac18a48966f230797567b302 |
| publicationDate | 2003-06-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2188225-T3 |
| titleOfInvention | DIHYDRO- (1,2,3) TRIAZOL-- (4,5-D) DIPPIRIMIDIN-7-ONA- |
| abstract | Dihydro- [1, 2, 3] triazolo- [4,5-d] pyrimidin-7-ones of general formula (I) ** (Formula) ** in which R1 means cycloalkyl with 3 to 8 carbon atoms or a remainder of the formula, ** (Formula) ** in which R2 means straight or branched chain alkyl with up to 10 carbon atoms, which, if necessary, is substituted by hydroxy, E means a remainder of formula -CH2 -T, in which T means a linear or branched alkylene chain with up to 10 carbon atoms, R3 means hydrogen or aryl with 6 to 10 carbon atoms, which, if necessary, is substituted up to 3 times equally or different by halogen, hydroxy, nitro, trifluoromethyl or by straight or branched alkyl or alkoxy with up to 6 carbon atoms, respectively, A and D mean hydrogen, or A hydrogen and D hydroxy or A and D together mean a remainder of the formula = O, L means a remainder of the formula ** (Formula) ** aryl with 6 to 10 carbon atoms or an aromatic heterocycle, given e In the benzo-condensed case, from 5 to 7 elements with up to 3 heteroatoms of the S, N and / or O series, the above-mentioned cyclic systems under L being substituted up to 3 times the same or different by one or more of the following substituents: halogen , hydroxy, nitro, trifluoromethyl, carboxy, alkyl, alkoxy and straight or branched chain alkoxycarbonyl, with up to 6 carbon atoms, respectively, a remainder of the formula - (V) to-NR4R5, in which a means 0 or 1, V means a remainder of the formula -CO or -SO2, R4 and R5 are the same or different and mean hydrogen or straight or branched chain acyl or alkoxycarbonyl with up to 6 carbon atoms, respectively, or straight chain alkyl or branched with up to 6 carbon atoms, which, if necessary, is substituted by hydroxy, amino or straight chain or branched alkylamino or dialkylamino with up to 6 carbon atoms, respectively, or R4 and R5 form together with the nitrogen atom A he saturated 5 or 6 element tetracycle, which may contain, if necessary, another heteroatom of the S, O series or a remainder of the formula -NR6 and which, if necessary, is substituted by linear or branched chain alkoxycarbonyl with up to 6 carbon atoms, wherein R6 means hydrogen or straight or branched chain alkyl with up to 4 carbon atoms, and / or the cyclic systems indicated under L are, where appropriate, substituted by aryl with 6 to 10 carbon atoms and an aromatic heterocycle, if necessary benzocondensed, of 5 to 7 elements with up to 3 heteroatoms of the S, N and / or O series, these cyclic systems being substituted in turn, if necessary, up to 2 times equally or distinct by substituents of the halogen, hydroxy, nitro, carboxyl, trifluoromethyl or alkyl, alkoxy or alkoxycarbonyl straight or branched chain chain with up to 5 carbon atoms, respectively, or by a group of the formula - (V ¿) b- NR7R8, in which b has the meaning or above indicated of a and is equal to or different from it, R7 and R8 have the above indicated meaning of R4 and R5 and are the same or different from this, V does the above indicated meaning of V and is the same or different from it, and the tautomers and salts thereof. |
| priorityDate | 1998-08-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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