http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2328601-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132aa5ddba376cda52c2bedb26765245 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 |
| filingDate | 2005-06-28^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71dc8cac27483b065f2da60e21bdc46a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a58b7262b06610322bc616aaa4bed9d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76e9b51e5908d7b59d707e886b5ee74f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee13c5f5ee32a0a9801cca5b9d3fa06d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81d2bb711ca4594b95c9e3eb8cc47637 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee35ecfbbbea7f607c700c5d9fbc1001 |
| publicationDate | 2009-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2328601-T3 |
| titleOfInvention | 4,6-DISPOSED PYRIMIDINES AND ITS USE AS PROTEIN CINASE INHIBITORS. |
| abstract | Compounds of formula I ** (See formula) ** in which R 1 is dibenzofuran-4-yl, dibenzothiophene-4-yl, 4-benzyloxy-phenyl, 4-phenoxy-phenyl, or tiantren-1-yl, R2 is hydrogen, or methyl, R3 is -U-Ar2, -V-Har2, or 2-amino-phenyl, in which U is a bond, and Ar2 is 3- (R31) -phenyl, 4- (R31) -phenyl , or 3- (R31) - or 4- (R31) -fluorophenyl, wherein R31 is C1-4 alkoxy, C1-4 alkyl, cyano, chloro, amidino, -W-R311, pyrrolidin-1-yl, or piperidin-3-yl, in which W is a bond, and R311 is -N (R312) R313, in which R312 is hydrogen, C1-4 alkyl, C1-4-alkoxy, or tert-butoxycarbonyl, R313 is hydrogen, or C1-4 alkyl, or W is methylene, ethylene, or 1,1-dimethylmethylene, R311 is -N (R312) R313, or bromine, wherein R312 is hydrogen, C1-4 alkyl, or tert-butoxycarbonyl, R313 is hydrogen, or C1-4 alkyl, or U is methylene, or ethylene, and Ar2 is phenyl, or 3- (R31) - or 4- (R31) -phenyl, wherein R31 is fluorine, C1-4 alkoxy, or aminomethyl, or U is a bond, or aminomethyl-methylene, and Ar2 is 3,4-dichlorophenyl, V is a link. Har2 is 1,2,3,4-tetrahydroisoquinolinyl, or pyridyl substituted with R33, wherein R33 is aminomethyl, or trifluoromethyl, and the salts of these compounds. |
| priorityDate | 2004-06-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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