http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2354929-T3
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Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b3db7dd56b56cc6d94d0e0cccc38322 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-412 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-678 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-922 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-9789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-9794 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-11 |
filingDate | 2008-07-04^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2011-03-21^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a93ee727d7a8c06f0c0cb29320f72832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f8802c058fd18a2d934d54d3d6c2103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a3b498a3998a0e65b08da6ae225647d |
publicationDate | 2011-03-21^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2354929-T3 |
titleOfInvention | NUCLEUS / CORTEZA TYPE CAPSULES AND PREPARATION PROCEDURE. |
abstract | Method of preparing a suspension of capsules of the core / cortex type comprising at least the following steps: a) providing a heterogeneous mixture at room temperature (Tamb) comprising: - an oil phase, - identical or different polymers, not miscible in water and in the oil phase, of which at least one polymer is an oligomer having a molecular weight by weight less than 10,000, and a hydroxyl number (lOH) greater than or equal to 10 mg KOH / g , b) homogenize the oil phase and the polymers by heating, at a homogenization temperature TH, of the mixture obtained in step a), TH being less than 100 ° C, said mixture having, at the temperature TH, a viscosity less than or equal to at 17 mPa.s -1, c) disperse, at temperature TH, the homogeneous mixture obtained in step b) in an aqueous phase, to obtain a direct pre-emulsion whose oil phase comprises the polymers, d) subject the pre -emulsion obtained in l to stage c) to a set of shear forces appropriate for the reduction of the diameter of the particles of the dispersed mixture to an average size of less than or equal to about 50 μm, and e) to cool the emulsion obtained in step d) to a temperature Tc suitable for the coacervation of said polymers and for the coating of drops of said oil phase by the coacervates, f) cooling the suspension obtained in step e) to a temperature Tp conducive to the formation of the capsules expected by precipitation and / or the crystallization of the coacervates, the oil phase being conducive to the formation of a homogeneous mixture with said polymers, at a temperature TH, and for the manifestation of a phenomenon of coacervation of said polymers at a temperature Tc. |
priorityDate | 2007-07-05^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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