http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2359836-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 |
| filingDate | 2005-04-22^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2011-05-27^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c7d79fb5c52ce1ed7914f0d4777bb88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_174c3d8236e0fc71e10f21285b3ae670 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8afc366f9b4d5fba8327ddedcf1a8874 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49409e38dea13f9d4cdcce4b47fc0e71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e96975b65e8ea41616ee1512ff894f8 |
| publicationDate | 2011-05-27^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2359836-T3 |
| titleOfInvention | MONOCICLIC HETEROCICLES AS QUINASA INHIBITORS. |
| abstract | A compound having Formula II: ** Formula ** or an enantiomer, a diastereomer or a pharmaceutically acceptable salt thereof, wherein: each R2 is independently H, halogen, cyano, NO2, OR5; NR6 R7, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, arylalkyl, substituted arylalkyl, heterocycloalkyl, or substituted heterocycloalkyl; B is O, S, SO, or SO2; W and X are each independently C or N; n is 0 to 4 if W and X are both C, 0 to 3 if one of X or W is N and 0 to 2 if X and W are both N; R3, R5, R6 and R7 are independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle; R4 is pyridinone, pyridyl, pyridyl-N-oxide, or optionally substituted pyrazolyl, provided that (a) if R4 is pyridyl, R4 is not substituted with hydroxy or with methoxy; A is selected from one of the following: ** Formula ** in which D is S or O; m is 0 to 6; R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26 and R27 are independently selected from H, halogen, NR30R31, OR32, CO2R33, SO2R36, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl , alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, -CN, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycloalkyl, or substituted heterocycloalkyl; R28 and R29 are independently H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, or are taken together to form a carbocyclic or heterocyclic ring of 3 to 8 atoms; and R30, R31, R32, R33 and R36 are independently H, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, cycloalkyl, substituted cycloalkyl, alkoxycarbonyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, heterocycle, substituted heterocycle, heterocycloalkyl, or substituted heterocycloalkyl. |
| priorityDate | 2004-04-23^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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