| abstract |
A compound of Formula (Ia), in which: R2 and R3 are independently selected from: - hydrogen, - halogen, - linear or branched C1-C6 alkyl, optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy, linear or branched C1-C6 alkoxy, phenoxy, - linear or branched C1-C6 alkoxy, - phenyl, optionally substituted with one or more substituents selected from the group consisting of halogen, hydroxy, linear or branched C1-C6 alkyl, - six-membered heterocyclic group having at least one heteroatom selected from nitrogen; R13 is selected from H, linear or branched C1-C6 alkyl; R14 is selected from linear or branched C1-C8 alkyl, optionally substituted with one or more halogen atoms and / or hydroxy groups, said C1-C8 alkyl optionally substituted by one or more unsaturated CC bonds or containing one or more oxygen atoms or sulfur in the alkyl chain, - C3-C8 cycloalkyl, optionally substituted with a linear or branched C1-C4 carboxy or alkoxycarbonyl group, - linear or branched C1-C6 alkyl phenyl, optionally said C1-C6 alkyl being an atom of oxygen, - a heterocyclic or heterocycloalkyl group selected from the group consisting of: 1,3-dioxolane, 2,2-dimethyl-1,3-dioxolane, thiophene, 1-methyl-1-morpholino-4-ylethyl, pyrimidine, pyridine , said pyridine optionally substituted with a hydroxy or C1-C6 alkoxy group; linear or branched pyridinyl-C1-C4 alkyl; piperidine, said piperidine optionally substituted with phenyl-C1-C4 alkyl; furan, tetrahydrofuran; Linear or branched 2-tetrahydrofuran-2-ylethyl, pyrrolidine N-carboxylic acid, N-alkoxycarbonylpyrrolidin-2-yl-C1-C4; tetrahydropyran; or R13 and R14, taken together, form a C3-C8 cycloalkyl; n is an integer selected between 0 and 1; as well as its geometric isomers, its optically active forms such as enantiomers, diastereomers, tautomers, racemates, and its pharmaceutically acceptable salts. |