| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b0c92a1c96d3aed697c64de10f37f47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da2fed3882a92d39a12a0120f1edcf59 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
| filingDate |
2010-06-01^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-01-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1edf7dba8b5ae18e4a635a8033513e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca8d064e13987bfb5e53694ed39af477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8983cb45c04c6a89f2d802abfa1ea510 |
| publicationDate |
2014-01-14^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2437751-T3 |
| titleOfInvention |
Procedures for synthesizing 3- (substituted dihydroisoindolinone-2-yl) -2,6-dioxopiperidine and intermediates thereof |
| abstract |
A process for synthesizing a compound of Formula (I): comprising reacting a compound of Formula (II) with a compound of Formula (III) to provide a compound of Formula (IV): in which: one of R, R3, R4 and R5 is amino or amino protected, nitro or halogen and the others are all hydrogen; X is halogen; Y is:> = O or H; Z is:> = O or H; and with the proviso that Y and Z are both> = O; or one of Y and Z is> = O and the other is H; R 'is an alkali metal ion or hydrogen or imine protecting group; A and B are each independently hydroxyl, C1-10 alkoxy, aryloxy, C1-4 arylalkoxy or NHR2 and in which R2 is hydrogen or amino protecting group; R1 is C1-4 alkyl or hydrogen. |
| priorityDate |
2009-06-01^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |