http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2463720-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40765ca9a78b54a8a76f781d159ad145 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 |
filingDate | 2008-11-13^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-05-29^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7e5150b00c90298cf0d6aea8cb76574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f7ca2e3099e109dfcbb2fcd668e7f3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1289dbe357d30967f4ccd4c9c0b0506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0628d48cfb7c639acbc3abd00511eed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_befa42d8e1ad50c564342af8ff3de610 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e3fd8298148ef5f8026fb2e42f20f84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8663b0a5d1baf670da9d6f7b30ead48f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_762c2ae24cdbd53d05833def75ed7908 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a43ff18c765d0080a0e35ccfb984ad2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24e4f690dad6769601120a9f6e66f5d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52e6a8219c3dd816f8910e3b7f2f33ee |
publicationDate | 2014-05-29^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2463720-T3 |
titleOfInvention | Human immunodeficiency virus replication inhibitors |
abstract | A compound of formula (I) and an isomer, racemate, enantiomer or diastereomer thereof: ** Formula ** in which ------- represents a single bond or a double bond; X is N when Y is N-R7; or X is N-R6 when Y is N; R2 and R5 are each independently selected from a) halo; b) R8, -C (> = O) -R8, -C (> = O) -O-R8, -O-R8, -S-R8, -SO-R8, -SO2-R8, -C1-alkylene - 6) -R8, -C1-6 alkylene-C (> = O) -R8, -C1-6 alkylene -C (> = O) -O-R8, -C1-6 alkylene - O-R8, -C1-6 alkylene-S-R8, -C1-6alkylene-SO-R8 or -C1-6 alkylene-SO2-R8; wherein R8 is independently selected in each case from H, (C1-6) alkyl, (C2-6) alkenyl, (C2-6) alkynyl, (C1-6) haloalkyl, (C3-7) cycloalkyl, aryl and Het; and wherein each of the aryl and Het is optionally substituted with from 1 to 3 substituents each independently selected from: i) halo, oxo, thioxo, (C2-6) alkenyl, halo (C1-6) alkyl, cycloalkyl ( C3-7), (C3-7) cycloalkyl-(C1-6) alkyl -, -OH, -O-C1-6alkyl, O-halo (C1-6 )alkyl, -SH, -S-alkyl ( C1-6), -SO-C1-6alkyl, -SO2-C1-6alkyl, -NH2, -NH-C1-6alkyl and -N ((C1-6alkyl) 2; ii) (C1-6) alkyl optionally substituted with -OH, -O-halo (C1-6) alkyl or -O-C1-6 alkyl; and iii) aryl or Het, where each of the aryl and Het is optionally substituted with halo or (C1-6) alkyl; and c) -N (R9) R10, -C (> = O) -N (R9) R10, -OC (> = O) -N (R9) R10, -SO2-N (R9) R10, -C1-alkylene - 6) -N (R9) R10, -C1-6 alkylene-C (> = O) -N (R9) R10, -C1-6 alkylene -OC (> = O) -N (R9) R10 or -C1-6 alkylene-SO2-N (R9) R10 wherein R9 is in each case independently selected from H, (C1-6) alkyl and (C3-7) cycloalkyl; and R10 is independently selected in each case from R8, -C1-6alkylene-R8, -SO2-R8, -C (> = O) -R8, - C (> = O) OR8 and -C ( > = O) N (R9) R8; where R3 and R9 are as previously defined. |
priorityDate | 2007-11-16^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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