http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2526567-T3

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a829bb36fd4d5fe133d7cca4bc984c1
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filingDate 2010-11-17^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-01-13^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b86fd27ea494ddf984e3538fdae4f2ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4691bb96efc5443b733b0d78251cb098
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publicationDate 2015-01-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2526567-T3
titleOfInvention Azaheterocyclic acrylamides and their use as bactericides
abstract A compound that is a compound of formula (I): ** Formula ** in which: W and X independently represent a bond or a group - (CH2) 1-4, such that W and X together contain 1- 5 carbon atoms; R1 represents an H, F, CN, (C1-C6) alkyl (C2-C6) alkenyl, (C2-C6) alkynyl, CO2Rd, CORd, CONRaRb, OCORd, ORd, NRaRb, ON> = CRdRe, NRcCORd, NRcCOORd, OCONRaRb, NRcCONRaRb, NRcSO2Ra, S (O) nRa, SO2NRaRb, - C (Ra)> = NO-Rf, Y-Ar or a Z-Het group, where Ar represents phenyl or naphthyl, Het represents a monocyclic or bicyclic heterocycle 4-10 saturated or unsaturated members, containing 1-5 heteroatoms selected from N, O and S, and Y and Z independently represent a bond or linker selected from O, S, CO, (C1-C6) alkylene, - O-C1-C6 alkylene -CO-C1-C6 alkylene or -ON> = CRd-C1-C6 alkylene, wherein said R1 group may be optionally substituted by one or more R4 groups; - R2 represents a group H, F, CN, (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, CO2Rd, CORd, CONRaRb, OCORd, ORd, NRaRb, ON> = CRdRe, NRcCORd , NRcCOORd, OCONRaRb, NRcCONRaRb, NRcSO2Ra, S (O) nRa or SO2NRaRb; - Ra, Rb and Rc independently represent H, (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, or an NRaRb group which may optionally form a saturated 3-7-membered nitrogen-containing heterocycle , which optionally contains 1 to 3 additional heteroatoms selected from N, O or S, wherein said heterocycle may be optionally substituted with one or more (C1-C6) alkyl groups; - Rd and Re independently represent H, (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, halo (C1-C6) alkyl, halo (C1-C6) alkyl -O-alkyl (C1-C6) or (C1-C6) alkyl -O-(C1-C6) alkyl; - Rf represents (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, halo (C1-C6) alkyl or (C1-C6) -Ar alkyl, wherein Ar represents phenyl or naphthyl ; - R4 represents halogen, CN, (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl, CO2Rd, CORd, CONRaRb, OCORd, ORd, NRaRb, ON> = CRdRe, NRcCORd, NRcCOORd, OCONRaRb, NRcCONRaRb, NRcSO2Ra, S (O) nRa or SO2NRaRb; - n represents an integer selected between 0 and 2; - R3 is a pyridyl ring optionally fused to a 5, 6 or 7 membered heterocycle containing 1-3 heteroatoms selected from N, O and S, wherein said heterocycle is aromatic, partially aromatic or saturated, and wherein said group R3 it may be optionally substituted with one or more R5 groups; - R5 is selected from the group consisting of F, CO2Rd, CORd, CONRaRb, ORd,> = O, NRaRb, NRcCORd or (C1- C6) alkyl optionally substituted with F, CO2Rd, CONRaRb, ORd, NRaRb, NRaCORd or Het optionally substituted with one or more (C1-C6) alkyl groups, or two R5 groups together with the atom to which they are attached can form a Het group optionally substituted with one or more (C1-C6) alkyl groups; or its pharmaceutically acceptable salt or solvate, with the proviso that the compound is other than 3- [6- (Benzo [b] thiophene-2-yl) -pyridin-2-yl] -1- (piperidin-1 acid salt) -yl) -propenone trifluoroacetic acid or 3- (6-Benzo [b] thiophen-2-yl) -pyridin-3-yl) -1- (piperidin-1-yl) propenone.
priorityDate 2009-11-18^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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