http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2538839-T3

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filingDate 2010-04-28^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-06-24^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38efeb06f126cd90a8941092fcdd6b2d
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publicationDate 2015-06-24^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2538839-T3
titleOfInvention Purine derivative and antitumor agent that uses it
abstract A compound represented by the formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof: ** Formula ** where Ar represents a phenyl group, a pyridyl group, a thiazolyl group, a benzofuranyl group, a group dihydrobenzofuranyl, a naphthalenyl group, an imidazolyl group or a pyrazolyl group that can be independently substituted with one, two or three halogens, formyl groups, cyano groups, nitro groups, amino groups, hydroxyl groups or carboxyl groups; or with one, two or three (C1-C6) alkyl groups, (C2-C6) alkenyl groups, (C1-C6) alkylcarbonyl groups, (C1-C6) alkylamino groups, (C1-C6) alkylcarbonylaminocarbonyl groups, (C3 -C6) cycloalkylamino, (C1-C7) alkoxycarbonylamino groups, di [(C1-C6) alkyl] amino groups, (C1-C6) alkylcarbonylamino groups, (C3-C6) cycloalkylcarbonylamino groups, di [(C1-C6) alkyl groups ] aminocarbonylamino, di [(C1-C6) alkyl] aminothiocarbonylamino groups, heteroarylcarbonylamino groups, phenyloxycarbonylamino groups, phenylcarbonylamino groups, (C1-C6) alkylsulfonylamino groups, di [(C1-C6) alkyl] aminosulfonyloamino groups, (C1-C6) groups alkoxy, (C1-C6) alkylthio groups, (C1-C6) alkylenedioxy groups, (C1-C6) alkoxycarbonyl groups, amino (C1-C6) alkylcarbonylamino groups, (C2-C6) alkenylcarbonylamino groups, (C1-C6) groups (C1-C6) alkoxycarbonylamino, (C1-C6) alkoxycarbonylamino (C1-C6) alkylcarbonylamino, phenyl groups or phenyl (C1-C6) alkoxy groups which may be substituted s with a halogen, a cyano group, an amino group, a hydroxyl group or a carboxyl group; Y represents a (C1-C6) alkylene group which may contain a carbonyl group in the carbon chain and / or may be substituted with one or two of Ar; R1 represents a (C1-C6) alkyl group or a (C2-C6) alkenyl group; or an amino group substituted with one or two (C1-C6) alkyl groups, (C1-C6) alkoxy groups, (C1-C6) alkoxy (C1-C6) alkyl groups, (C3-C6) cycloalkyl groups or (C2) groups -C6) alkenyl; or a (C1-C6) alkylcarbonylamino group which may be substituted with one or two (C1-C6) alkyl groups, (C1-C6) alkoxy groups, (C1-C6) alkoxy (C1-C6) alkyl groups, (C3) groups -C6) cycloalkyl or (C2-C6) alkenyl groups; or a heterocyclic group which may be substituted with one or two nitroso groups, formyl groups, hydroxyl groups, (C1-C6) alkyl groups, (C1-C6) alkylcarbonyl groups, (C1-C6) alkoxy groups, (C1-C6 groups ) alkoxycarbonyl or hydroxy (C1-C6) alkylamino groups; or a phenyl group substituted with a halogen, a formyl group, a cyano group, a nitro group, an amino group, a hydroxyl group, (C3-C6) or a carboxyl group, R2 represents H; or a (C1-C6) alkyl group, a (C2-C6) alkenyl group, a (C2-C6) alkynyl group or a (C3-C6) cycloalkyl group which may be substituted with one or two halogens, nitro groups or groups Not me; and R3 represents a (C1-C6) alkyl group, a (C2-C6) alkenyl group, a (C2-C6) alkynyl group, a (C3-C6) cycloalkyl group, a (C3-C6) cycloalkyl (C1-) group C6) alkyl, an amino (C1-C6) alkyl group, an ether group (C1-C6) alkyl of three to five members or a (C1-C6) alkylcarbonylamino (C1-C6) alkyl group which may be substituted with a halogen or a hydroxyl group.
priorityDate 2009-04-28^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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