http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2538839-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34243ed5d528597b57990d6901da658f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2010-04-28^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-06-24^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38efeb06f126cd90a8941092fcdd6b2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_863b198c801101fc7612780b24df1c71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_998b34a223512b69f49fc193ee4f35a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e828a46187bd372ddadf2fcea7ae453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f864e743603a545f60143293c5311f78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d3fbb9d75b38edc4136b8e7ac368fd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aba25cda3a77d104e0dbee67e3975864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cdc4824de8b956adad0dcd9adf021de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e9f1583935b71d8269a62355e0aa3ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2db51dca9e99f88ce060adcb5fd1ed82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d3f51b8cf0dddd9d0506f763a4b7cb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2594aa76b2a45db47fb2f47046e2712e |
publicationDate | 2015-06-24^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2538839-T3 |
titleOfInvention | Purine derivative and antitumor agent that uses it |
abstract | A compound represented by the formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof: ** Formula ** where Ar represents a phenyl group, a pyridyl group, a thiazolyl group, a benzofuranyl group, a group dihydrobenzofuranyl, a naphthalenyl group, an imidazolyl group or a pyrazolyl group that can be independently substituted with one, two or three halogens, formyl groups, cyano groups, nitro groups, amino groups, hydroxyl groups or carboxyl groups; or with one, two or three (C1-C6) alkyl groups, (C2-C6) alkenyl groups, (C1-C6) alkylcarbonyl groups, (C1-C6) alkylamino groups, (C1-C6) alkylcarbonylaminocarbonyl groups, (C3 -C6) cycloalkylamino, (C1-C7) alkoxycarbonylamino groups, di [(C1-C6) alkyl] amino groups, (C1-C6) alkylcarbonylamino groups, (C3-C6) cycloalkylcarbonylamino groups, di [(C1-C6) alkyl groups ] aminocarbonylamino, di [(C1-C6) alkyl] aminothiocarbonylamino groups, heteroarylcarbonylamino groups, phenyloxycarbonylamino groups, phenylcarbonylamino groups, (C1-C6) alkylsulfonylamino groups, di [(C1-C6) alkyl] aminosulfonyloamino groups, (C1-C6) groups alkoxy, (C1-C6) alkylthio groups, (C1-C6) alkylenedioxy groups, (C1-C6) alkoxycarbonyl groups, amino (C1-C6) alkylcarbonylamino groups, (C2-C6) alkenylcarbonylamino groups, (C1-C6) groups (C1-C6) alkoxycarbonylamino, (C1-C6) alkoxycarbonylamino (C1-C6) alkylcarbonylamino, phenyl groups or phenyl (C1-C6) alkoxy groups which may be substituted s with a halogen, a cyano group, an amino group, a hydroxyl group or a carboxyl group; Y represents a (C1-C6) alkylene group which may contain a carbonyl group in the carbon chain and / or may be substituted with one or two of Ar; R1 represents a (C1-C6) alkyl group or a (C2-C6) alkenyl group; or an amino group substituted with one or two (C1-C6) alkyl groups, (C1-C6) alkoxy groups, (C1-C6) alkoxy (C1-C6) alkyl groups, (C3-C6) cycloalkyl groups or (C2) groups -C6) alkenyl; or a (C1-C6) alkylcarbonylamino group which may be substituted with one or two (C1-C6) alkyl groups, (C1-C6) alkoxy groups, (C1-C6) alkoxy (C1-C6) alkyl groups, (C3) groups -C6) cycloalkyl or (C2-C6) alkenyl groups; or a heterocyclic group which may be substituted with one or two nitroso groups, formyl groups, hydroxyl groups, (C1-C6) alkyl groups, (C1-C6) alkylcarbonyl groups, (C1-C6) alkoxy groups, (C1-C6 groups ) alkoxycarbonyl or hydroxy (C1-C6) alkylamino groups; or a phenyl group substituted with a halogen, a formyl group, a cyano group, a nitro group, an amino group, a hydroxyl group, (C3-C6) or a carboxyl group, R2 represents H; or a (C1-C6) alkyl group, a (C2-C6) alkenyl group, a (C2-C6) alkynyl group or a (C3-C6) cycloalkyl group which may be substituted with one or two halogens, nitro groups or groups Not me; and R3 represents a (C1-C6) alkyl group, a (C2-C6) alkenyl group, a (C2-C6) alkynyl group, a (C3-C6) cycloalkyl group, a (C3-C6) cycloalkyl (C1-) group C6) alkyl, an amino (C1-C6) alkyl group, an ether group (C1-C6) alkyl of three to five members or a (C1-C6) alkylcarbonylamino (C1-C6) alkyl group which may be substituted with a halogen or a hydroxyl group. |
priorityDate | 2009-04-28^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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