| abstract |
A monoclonal antibody comprising an antigen binding domain, said antibody being capable of binding with an epitope of an RGM molecule, said antigen domain comprising a heavy chain variable domain having at least three complementarity determining regions and a domain light chain variable having at least three complementarity determining regions, where the complementarity determining regions of the heavy chain variable domain have the amino acid sequence of SEQ ID NO: 57, SEQ ID NO: 58 and SEQ ID NO: 59 and where the complementarity determining regions of the light chain variable domain have the amino acid sequence of SEQ ID N: 60, SEQ ID N: 61 and SEQ ID N: 62. |