http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2675798-T3

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filingDate 2010-10-15^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-07-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b188628d59416acd95346bf36e2873
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publicationDate 2018-07-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2675798-T3
titleOfInvention Antimicrobial compounds and methods for manufacturing and using them
abstract A compound having the formula: ** Formula ** in which -GHJ, alternatively, is ** Formula ** in which each H and J are independently selected, D and E are single bonds and F is hydrogen, CBA - and -GHJ are chemical moieties, in which A is selected from (a) a 3-14 membered saturated, unsaturated or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen and sulfur, and (b) a 3-14 membered saturated, unsaturated or aromatic carbocycle, in which (a) or (b) is optionally substituted with one or more R5 groups; G is (a) a 3-14 membered saturated, unsaturated or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, or (b) a 3-14 saturated, unsaturated or aromatic carbocycle members, in which (a) or (b) is optionally substituted with one or more R5 groups; H is selected from the group consisting of: (a) a single bond; (b) a 3-14 membered saturated, unsaturated or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, (c) a 3-14 membered saturated, unsaturated or aromatic carbocycle in which (b) or (c) is optionally substituted with one or more R5 groups; (d) - (C1-8alkyl) -, (e) - (C2-8alkenyl) -, (f) - (C2-8alkynyl) -, where i) 0-4 carbon atoms in any of (d) - (f) immediately above are optionally replaced by a residue selected from the group consisting of -O-, -S (O) p-, -NR6-, - (C> = O) -, - C (> = NR6) -, -S (O) pNR6-, -NR6S (O) p-, and NR6S (O) pNR6-, ii) any of (d) - (f) immediately above is optionally substituted with one or more groups R5, and iii) any of (d) - (f) immediately above is optionally substituted with groups - (C1-8 alkyl) -R5; and (g) - (CR6R6) t-, B is (a) - (C1-8 alkyl) -, (b) - (C2-8 alkenyl) -, (c) - (C2-8 alkynyl) -, or (d) a single bond, where i) 0-4 carbon atoms in any of (a) - (c) immediately above are optionally replaced by a residue selected from the group consisting of -O-, -S (O) p -, -NR6-, - (C> = O) -, -C (> = NR6) -, -S (O) pNR6-, and - NR6S (O) pNR6-, ii) any of (a) - ( c) immediately above is optionally substituted with one or more R5 groups, and / or iii) any of (a) - (c) immediately above is optionally substituted with - (C1-8 alkyl) -R5 groups; C and J are independently selected from the group consisting of: (a) hydrogen, (c) F, (d) Cl, (e) Br, (f) I, (g) -CF3, (h) -CN, ( i) -N3 (j) NO2, (k) -NR6 (CR6R6) tR8, (l) -OR8, (m) - S (O) p (CR6R6) tR8, (n) -C (O) (CR6R6) tR8, (o) -OC (O) (CR6R6) tR8, (p) -SC (O) (CR6R6) tR8, (q) -C (O) O (CR6R6) tR8, (r) - NR6C (O) (CR6R6) tR8, (s) -C (O) NR6 (CR6R6) tR8, (t) -C (> = NR6) (CR6R6) tR8, (u) -C (> = NN6R6) (CR6R6) tR8, ( v) - C (> = NNR6C (O) R6) (CR6R6) tR8, (w) -C (> = NOR8) (CR6R6) tR8, (x) NR6C (O) O (CR6R6) tR8, (y) - OC (O) NR6 (CR6R6) tR8, (z) -NR6C (O) NR6 (CR6R6) tR8, (aa) NR6S (O) p (CR6R6) tR8, (bb) -S (O) pNR6 (CR6R6) tR8 , (cc) - NR6S (O) pNR6 (CR6R6) tR8, (dd) -NR6R8, (ee) -NR6 (CR6R6) R8, (ff) -OH, (gg) -NR8R8, (hh) -OCH3, ( ii) -S (O) pR8, (jj) -NC (O) R8, (kk) -NR6C (NR6) NR6R8, (11) C1-8 alkyl, (mm) C2-8 alkenyl, (nn) C2 alkynyl -8, (oo) a 3-14 membered saturated, unsaturated, or aromatic heterocycle containing one or more heteroatoms selected from the group consisting of nitrogen, oxygen, and sulfur, (pp) a saturated, unsaturated carbocycle 3-14 membered aromatic oo, (qq) - (CR6R6) tNR6 (CR6R6) tR8, (rr) -N [(CR6R6) tR8] [C> = O (CR6R6) tR8], (ss) - (CR6R6) tN [(CR6R6) tR8] [(CR6R6) tR8], (tt) - (CR6R6) tNR6 (C> = O) (CR6R6) tR8, (uu) -haloalkyl, (w) - C (O) (CR6) [(CR6R6) tR8] R8, (ww) - (CR6R6) tC (O) NR8R8, (xx) - (CR6R6) tC (O) O (CR6R6) tR8, (yy) NR6C (O) CR8R8R8, (zz) -N [(CR6R6) tR8] C (O) R8, and (aaa) -S (O) pNR8R8
priorityDate 2009-10-16^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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