abstract |
The use of secreted phospholipase A2 (sPLA2) and / or at least one metabolite produced by said sPLA2, capable of modulating fertilization, for the manufacture of an anti-sterility drug, or of a drug that promotes or improves fertilization, or of a drug that promotes or improves a viable embryogenesis, or of a contraceptive drug, wherein said at least one metabolite is selected from the list consisting of arachidonic acid, myristoleic acid, palmitoleic acid, sapienic acid, oleic acid, linoleic acid, α- linolenic, eicosapentaenoic acid, docosahexaenoic acid, lysophosphatidylcholine, lysophosphatidylethanolamine, lysophosphatidylserine, lysophosphatidylinositol, lysophosphatidylglycerol, lysophosphatidate. |