| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
2013-08-30^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-11-04^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf457006aa2d8341c3f4253c1fdb942 |
| publicationDate |
2019-11-04^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2729561-T3 |
| titleOfInvention |
Transfer of the aquaporin gene mediated by an adeno-associated virus (aav) for the treatment of Sjögren's syndrome |
| abstract |
A composition for use (i) in the treatment of Sjögren's syndrome or (ii) in the prevention of xerostomia or xerophthalmia associated with Sjögren's syndrome, the composition comprising an AAV expression vector encoding a protein comprising the amino acid sequence of an aquaporin protein (AQP) or an AAV virion comprising the AAV vector, where administration of the composition to a subject (i) relieves at least one symptom of xerostomia or xerophthalmia associated with the syndrome de Sjögren or (ii) protects the subject from xerostomia or xerophthalmia associated with Sjögren's syndrome. |
| priorityDate |
2012-08-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |