http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2763526-T3

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filingDate 2015-07-02^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-29^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dbfb59173b7ee32c6bc4c526f59379f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7682928e797c4d6a4877b070f43de03
publicationDate 2020-05-29^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2763526-T3
titleOfInvention Polypeptide expression systems
abstract A polypeptide expression system comprising a first nucleic acid molecule and a second nucleic acid molecule, wherein: (a) the first nucleic acid molecule comprises a first expression cassette comprising the following components: (i) a first eukaryotic promoter (P1Euk1), (ii) a first polypeptide-encoding sequence (PES11), (iii) a first 5 'splice site (5'ss11) and (iv) a hybridization sequence (HS1), in that the components are functionally linked to each other in the 5 'to 3' direction as P1Euk1-PES11-5'ss11-HS1; wherein the first expression cassette further comprises a cleavable prokaryotic promoter module (ePPM1) comprising the following components: (i) a 5 'splice site (5'ss12), (ii) a prokaryotic promoter (P1Prok1) and (iii) a 3 'splice site (3'ss11), in which the components are functionally linked to each other in the 5' to 2 'direction as 5'ss13-P1Prok1-3'ss11, and in the that ePPM1 is located between P1Euk1 and PES11, and (b) the second nucleic acid molecule comprises the following components: (i) a eukaryotic promoter (P2Euk), (ii) a hybridization sequence capable of hybridizing with HS1 ( HS2), (iii) a 3 'splice site (3'ss2), (iv) a polypeptide-encoding sequence (PES2), and (v) a polyadenylation site (pA2), in which the components are linked functional to each other in the 5 'to 3' direction as P2Euk-HS2-3'ss2-PES2-pA2.
priorityDate 2014-07-03^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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