| abstract |
A compound, or a tautomer thereof, or a stereoisomer of said compound or of said tautomer, or a pharmaceutically acceptable salt thereof, said compound having the structural Formula (II): ** (See formula) ** where: - L1- represents a bond; -L3- is -C (O) NH-; m, n, and p are each independently selected integers, where: m is 0 or more; n is 1; and p is 0 or more, where the maximum value of the sum of m and n is the maximum number of substitutable hydrogen atoms available in ring A and where the maximum value of p is the maximum number of substitutable hydrogen atoms available in the ring. ring B; R3 is H; Ring A is selected from the group consisting of phenyl, pyridyl, pyrazinyl, furanyl, thienyl, pyrimidinyl, pyridazinyl, thiazolyl, oxazolyl, benzothienyl, benzimidazolyl, indazolyl, indolyl, and thienopyrazolyl; Each R5 group (when present) is independently selected from the group consisting of halogen, -CN, -SF5, -N (R8) 2, -OR7, -SR7, C1-6 alkyl, C1-6 haloalkyl , C 1-6 heteroalkyl, C 2-6 alkynyl and cycloalkyl; each R7 (when present) is independently selected from the group consisting of H, alkyl, alkenyl, heteroalkyl, haloalkyl, aryl, arylalkyl-, heteroaryl, heteroarylalkyl-, cycloalkyl, cycloalkylalkyl-, heterocycloalkyl, and heterocycloalkylalkyl-; Each R8 (when present) is independently selected from the group consisting of H, alkyl, alkenyl, heteroalkyl, haloalkyl, haloalkenyl, aryl, arylalkyl-, heteroaryl, heteroarylalkyl-, cycloalkyl, cycloalkylalkyl-, heterocycloalkyl, and heterocycloalkylalkyl- ; Ring B is selected from the group consisting of phenyl, pyridyl, pyrazinyl, furanyl, thienyl, pyrimidinyl, pyridazinyl, thiazolyl, oxazolyl, isoxazolyl, isothiazolyl, indolyl, pyrrolopyridyl, and pyrrolopyrimidinyl; and each R9 group (when present) is independently selected from the group consisting of halogen, -CN, -SF5, -N (R8) 2, -OR7, -SR7, C1-6 alkyl, C1- haloalkyl 6, C 1-6 heteroalkyl, C 2-6 alkynyl, phenyl, benzyl, and cycloalkyl. |