http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2804545-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d12fcf94a35348198bf31558dcff2cf6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-94 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2014-03-11^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab46286ee11be8ccc6a0b0bff34ea0cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7df49fa20e588e206244d017223925e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf759386262daa00f0413afa2d6efa9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c2d11807aa60d037a3fdccbf93d2096 |
| publicationDate | 2021-02-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2804545-T3 |
| titleOfInvention | New modulators of 5-hydroxytryptamine 7 receptor activity and their method of use |
| abstract | A compound selected from the group consisting of: 2- (4- (2- (4,4-diethyl-5-oxotetrahydrofuran-2-yl) ethyl) piperazin-1-yl) benzonitrile; 3,3-diethyl-5- (2- (4- (4-methoxyphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (4-hydroxyphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (4-nitrophenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (2-methoxyphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 4- (4- (2- (4,4-diethyl-5-oxotetrahydrofuran-2-yl) ethyl) piperazin-1-yl) benzonitrile; 3,3-diethyl-5- (2- (4- (2-hydroxyphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 5- (2- (4- (4-aminophenyl) piperazin-1-yl) ethyl) -3,3-diethyldihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (p-tolyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (3-methoxyphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (3-hydroxyphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 5- (2- (4- (2,6-dimethylphenyl) piperazin-1-yl) ethyl) -3,3-diethyldihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (o-tolyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 3,3-diethyl-5- (2- (4- (2-isopropylphenyl) piperazin-1-yl) ethyl) dihydrofuran-2 (3H) -one; 5- (2- (4- (2,4-dimethylphenyl) piperazin-1-yl) ethyl) -3,3-diethyldihydrofuran-2 (3H) -one; 3- (2- (4- (2-isopropylphenyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; 3- (2- (4- (2- (tert-butyl) phenyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; 3- (2- (4- (2,6-diisopropylphenyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; 3- (2- (4- (2-morpholinophenyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; 3- (2- (4 - ([1,1'-biphenyl] -2-yl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; 3- (2- (4- (2- (1H-pyrrol-1-yl) phenyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; 3- (2- (4- (2-iodophenyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; N- (2- (4- (2- (1-oxo-2-oxaspiro [4.4] nonan-3-yl) ethyl) piperazin-1-yl) phenyl) acetamide; 5-nitro-2- (4- (2- (1-oxo-2-oxaspiro [4.4] nonan-3-yl) ethyl) piperazin-1-yl) benzonitrile; and 3- (2- (4- (p-tolyl) piperazin-1-yl) ethyl) -2-oxaspiro [4.4] nonan-1-one; or a pharmaceutically acceptable derivative salt. |
| priorityDate | 2013-03-11^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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