http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2864999-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-721 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate | 2017-08-18^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c2096060fd409952a98621967fcd5df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1dc94af9b487a7eabafc8b56c92e0ef3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85a49b5b9402ab218abfaef95b7fc2d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9cf4ea58b53c971ff0c969f342381d5 |
| publicationDate | 2021-10-14^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2864999-T3 |
| titleOfInvention | Allele-specific multiplex PCR assays for the detection of mutations in the estrogen receptor ESR1 |
| abstract | A kit comprising three vessels, in which: (i) a first vessel contains a primer pair specific for ESR1 V422DelV, a primer pair specific for ESR1 S463P, a primer pair specific for ESR1 L536H, a primer pair specific for ESR1 L536P, one primer pair specific for ESR1 L536Q, one primer pair specific for ESR1 L536R and one primer pair specific for ESR1 D538G; (ii) a second container contains a primer pair specific for ESR1 K303R, a primer pair specific for ESR1 E380Q, a primer pair specific for ESR1 L536_D538> P, a primer pair specific for ESR1 Y537C, a primer pair specific for ESR1 Y537N and a primer pair specific for ESR1 Y537S; and (iii) a third container contains a primer pair specific for ESR1 S341L, a primer pair specific for ESR1 L429V, a primer pair specific for ESR1 V533M, a primer pair specific for ESR1 V534E, and a primer pair specific for ESR1 P535H; each of the containers containing two or more probes specific for a different sequence of the ESR1 gene, wherein each probe is labeled with a fluorophore and a quencher; a primer pair specific for an internal control sequence; and a probe specific for the internal control sequence and labeled with a fluorophore and a quencher; and wherein the containers comprise oligonucleotides having the sequences of SEQ ID NO: 24, 113, 134, 158, 178, 264, 261, 262, 285, 286, 298, 314, 394, 407, 31, 42, 90 , 415, 447, 469, 476, 477, 481, 528, 59, 60, 70, 231, 235, 237, 245, 350 and 388. |
| priorityDate | 2016-08-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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