http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-310875-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36b5c496f6aec894819ec2acaedb4203 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- |
| filingDate | 1965-03-23^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1965-06-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-310875-A1 |
| titleOfInvention | A PROCEDURE FOR THE PREPARATION OF NEW NITROGENATED STEROIDS. |
| abstract | A process for the preparation of compounds of general formula I: ** (See formula) ** wherein R represents hydrogen, a lower alkyl radical or the acyl radical of a lower organic acid, and salts of said compounds, characterized in that a secondary amine, especially dimethylamine, is condensed on the chloride of beta-5-acid. cholanic esterified in position 3, is obtained with simultaneous saponification the 3 alpha-hydroxy 24-oxo 25-aza 5 beta-cholestane, is subjected to the action of an oxidizing agent, which leads to 3,24-dioxo 25-aza 5 beta-cholestane, the system of two double bonds in positions 1 and 4 is introduced by bromination and dehydromination. The 3,24-dioxo-25-aza-1,4-cholestadiene obtained by 3-hydroxy 24- is aromatized by thermolysis. oxo 25-aza 19-nor 1,3,5 (10) -colestatriene, which, by the action of a reducing agent, provides the 3-hydroxy 25-aza 19-nor 1,3,5 (IO) -colestatriene sought and, when the cas1 is converted, this latter compound is converted into the desired functional derivative of general formula I. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1964-03-27^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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