abstract |
THE DERIVATIVES OF ISOXAZOLE AND FURANE (I), WHERE NOT EXCLUSIVELY, AND IS AN ALKYLENE BRIDGE C3-9 OPTIONALLY INTERRUPTED BY AN INSATURATION, Z IS NITROGEN OR R5C, R5 LOWER ALCANOYL, R LOWER ALKYL, AND R1 OR R1 THEY ARE HALOGEN, NITRO OR TRIFLUOROMETHYL, R3 AND R4 LOWER ALKYL C1-3; IT IS OBTAINED BY REACTING A COMPOUND (II), WHERE HA1 IS CHLORINE, BROMINE OR IODINE WITH AN ALKALINE METAL SALT, OF ANOTHER (III), IN THE PRESENCE OF A BASE SUCH AS CARBONATE, HYDROXIDE, METOXIDE, SODIUM OR POTASSIUM AND A SOLVENT INERT LIKE DIOXANE OR BENZENE. THEY ARE ANTIVIRAL AGENTS. * FORMULA * L |