| abstract |
THE INVENTION CONCERNS ANTIBIOTICS OF BETAINS OF CEPHALOSPORINS WITH LARGE SPECTRUM RESPONDING TO THE FORMULA: (CF DRAWING IN BOPI) OR R AND R EACH REPRESENT A HYDROGEN ATOM OR AN ALKYL GROUP IN CC AND R REPRESENTS A HETAGONALYL OR HETAGONALYL NUCLEUS SUBSTITUTED BY AN AMINO GROUP, FOR EXAMPLE, A 2-AMINOTHIAZOL-4-YLE CORE, AND R REPRESENTS A CC ALKYL GROUP, AN N-SUBSTITUTE CARBAMOYL GROUP OR AN ALKYL OR CYCLOALKYL GROUP SUBSTITUTED BY A CARBOX GROUP; THESE ANTIBIOTICS EXERCISE A POWERFUL ACTIVITY AGAINST GRAM-NEGATIVE ORGANISMS. |