| abstract |
A process for producing a bio-ink for additive deposition, in which a first solution comprising between 5% and 40% by weight of gelatin is supplied, a second solution comprising between 15% and 35% by weight of alginate, third solution comprising between 1% and 15% by weight of fibrinogen, and optionally living cells in suspension; and creating a mixture comprising: about 35% to 65% by volume of the first solution; about 15% to 35% by volume of the second solution; about 15% to 35% by volume of the third solution; these proportions being chosen so as to add up to 100%. This bio-ink allows the additive deposition of objects that can be polymerized with a solution comprising calcium ions and thrombin. These objects can be incubated and can be used as a substitute for body tissue, for example (with incorporated fibroblasts) as a skin substitute. |